Use LC-MS to Confirm Unknown Degradants in Advanced Stability Profiling
Understanding the Tip: The importance of identifying unknown degradation products: During long-term or accelerated stability studies, products may develop new or increasing impurities. While HPLC can detect these peaks, it often lacks the specificity to identify their structure. Liquid Chromatography–Mass Spectrometry (LC-MS) allows you to pinpoint the molecular mass and fragmentation pattern of unknown degradants,…
Read More “Use LC-MS to Confirm Unknown Degradants in Advanced Stability Profiling” »