Using High-Voltage Leak Detection in Parenteral Packaging
High-Voltage Leak Detection (HVLD) is a non-destructive, deterministic method widely adopted for container closure integrity testing (CCIT) in parenteral drug packaging. With its ability to detect submicron leaks in liquid-filled containers, HVLD is particularly useful in sterile dosage forms such as glass ampoules, prefilled syringes, and vials. In this tutorial, we discuss how HVLD works,…
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